1、Effective drug combinations in breast, colon and pancreatic

This study identifies clinically relevant effective drug combinations in distinct molecular subpopulations and is a resource to guide rational efforts to develop combinatorial drug treatments.

2、Brassinosteroids en route

Brassinosteroids (BRs) are hormones essential for plant growth and development across the entire life cycle 1. Together with BRs, other phytohormones, such as auxins and abscisic acid,...

3、Efficacy and safety of anticancer drug combinations: a meta

Our aim was to compare efficacy and safety of combination versus single non-cytotoxic anticancer agents.

4、Synergistic Effects of Natural Compounds Combinations in the

Combination therapy involving phytocompounds presents a promising frontier in management of breast cancer, capitalizing on the diverse bioactive attributes of plant-sourced substances.

Brassinosteroids Application Responses in Fruit Crops

Research findings on influences of exogenous BRs application on various aspects of growth and development like vegetative growth, flowering, fruit set, fruit growth, ripening, storage, and...

Anticancer Drug Combination, From Possibility to Principles

Since no principle of anticancer drug combinations is available for clinical cancer trials, some new suggestions should be raised to update drug combination optimization.

Cancer prevention and treatment using combination therapy with natural

Expert opinion: Combination therapy with natural compounds has the potential to be more effective than single agent therapy. Similar to pharmacologic agents, the goal is to maximize efficacy while mimimizing potential side effects.

Immunotherapy combination approaches: mechanisms, biomarkers and

Here, we present the rationale for combination therapies and discuss clinical data from clinical trials across the immuno-oncology spectrum.

Rational combinations of targeted cancer therapies: background

Here, we discuss the mechanisms of resistance to targeted therapies and how effective drug combinations can be identified to combat resistance. The challenges in clinically developing these...

Biological insights into effective and antagonistic combinations of

In this article, we review the preclinical molecular bases that justify approved combinations of targeted agents with chemotherapy including examples of synergistic and antagonistic combinations.

Brassinoids, also known as Bacillus thuringiensis (Bt), are natural microbial pesticides containing the bacteria Bacillus thuringiensis israelensis (Bti). This bacteria produces a protein called "toxin" which is highly toxic to certain insects. brassinoids are widely used in agricultural production to prevent and control pests on crops such as aphids, plant hoppers, and cotton bollworms.

while brassinoids are effective pesticides, they are not universally applicable. In practical applications, to enhance their efficacy, brassinoids are often combined with other drugs or methods. Here are some common combination schemes:

1. Combination with Chemical Pesticides: Brassinoids can be used together with chemical pesticides to improve control effects. For example, brassinoids can be mixed with chemicals like malathion and imidacloprid for better prevention and control.

2. Combination with Biopesticides: Brassinoids can be used alongside biopesticides to enhance effectiveness. For instance, combining brassinoids with biological pesticides such as avermectin and flubenoxazone can achieve better results.

3. Combination with Physical Methods: Brassinoids can also be used in conjunction with physical methods to increase effectiveness. Using traps like sticky boards or yellow boards with brassinoids can lead to better prevention and control.

4. Combination with Plant-Based Pesticides: Brassinoids can be combined with plant-based pesticides to improve efficacy. Mixing brassinoids with plant extracts like sophora alkaloid and tea saponin can provide better outcomes.

5. Combination with Soil Amendments: Brassinoids can also be used together with soil amendments to enhance effectiveness. For example, mixing brassinoids with organic fertilizers or biofertilizers can achieve better prevention and control.

6. Combination with Resistance Management Strategies: Brassinoids can be used in combination with resistance management strategies to improve effectiveness. Integrating brassinoids with resistance monitoring and management strategies can lead to better results.

brassinoids can be combined with various other agents or methods to enhance their prevention and control effects. When choosing a combination scheme, factors such as specific crops, pest types, and environmental conditions should be comprehensively considered to achieve the best prevention and control results. Additionally, when using brassinoids along with other pesticides or methods, strict adherence to relevant regulations and safe operating procedures is crucial to ensure the safety and sustainability of agricultural production.